What is the cause of strong itching from touch?

What is the cause of strong itching from touch?


What is the cause of strong itching from touch?
A study conducted on a group of experimental mice revealed that the loss of "receptor cells" can cause strong itching from just light touch, as suffering from a sharp interaction with light touch, as among older people, may be due to a decrease in the number of " Receptors "on the surface of the skin.

Researchers at the University of Washington have been studying severe itching from intense light exposure even when the skin is covered with clothing. In the course of their research, published in the May issue of the journal Science, researchers hope their research will develop a cure for this embarrassing condition .

"Touch-itching becomes more common as we age, a problem especially for people who have dry skin or who already suffer from chronic itching, it may be itching," said Hong Chen, an anesthesiologist at the University of Washington, in a press release. More than one source, while there are no medicines available for treatment for this type of itching, so we wanted to identify the causes of this itching in our quest to find better ways to treat them.

The researchers found that dry-skin animals had fewer receptors, and that the number of skin-receptors in the skin, called Merkel, had decreased as mice progressed.

It was observed that when Merkel's cells were activated among genetically modified mice using a chemical compound, they found that mice that were more susceptible to scratching when touched could overcome the itching caused by this scratching.

The researchers also found that a protein called piezo-2, which is produced on the membranes of Merkel cells, also plays a role in controlling the cells and reduce itching.

Dr Bryan S., "As people age, their skin changes, and for some people it can lead to severe and intractable itching. For example, many patients with severe, chronic itching associated with aging can not tolerate certain types of clothing "He said.

The researchers stressed the importance of the results obtained, which gives them some hope of controlling the activity of Merkel's own cells, so they can control the type of itching.

Researchers are now studying human skin samples among people with touch-related itching to see if the results will translate into human therapeutic methods.
What is the cause of strong itching from touch?
A study conducted on a group of experimental mice revealed that the loss of "receptor cells" can cause strong itching from just light touch, as suffering from a sharp interaction with light touch, as among older people, may be due to a decrease in the number of " Receptors "on the surface of the skin.

Researchers at the University of Washington have been studying severe itching from intense light exposure even when the skin is covered with clothing. In the course of their research, published in the May issue of the journal Science, researchers hope their research will develop a cure for this embarrassing condition .

"Touch-itching becomes more common as we age, a problem especially for people who have dry skin or who already suffer from chronic itching, it may be itching," said Hong Chen, an anesthesiologist at the University of Washington, in a press release. More than one source, while there are no medicines available for treatment for this type of itching, so we wanted to identify the causes of this itching in our quest to find better ways to treat them.

The researchers found that dry-skin animals had fewer receptors, and that the number of skin-receptors in the skin, called Merkel, had decreased as mice progressed.

It was observed that when Merkel's cells were activated among genetically modified mice using a chemical compound, they found that mice that were more susceptible to scratching when touched could overcome the itching caused by this scratching.

The researchers also found that a protein called piezo-2, which is produced on the membranes of Merkel cells, also plays a role in controlling the cells and reduce itching.

Dr Bryan S., "As people age, their skin changes, and for some people it can lead to severe and intractable itching. For example, many patients with severe, chronic itching associated with aging can not tolerate certain types of clothing "He said.

The researchers stressed the importance of the results obtained, which gives them some hope of controlling the activity of Merkel's own cells, so they can control the type of itching.

Researchers are now studying human skin samples among people with touch-related itching to see if the results will translate into human therapeutic methods.